Outcome Comparison Between Tocilizumab Alone Vs Tocilizumab Followed by Intravenous Immunoglobulin (IVIG) Group in Critical COVID-19 Disease
نویسندگان
چکیده
Currently, COVID-19 is one of the most pressing healthcare problems across world. With no definitive pharmacological guidelines, multiple drugs were used to treat critical patients with little success. Tocilizumab, a monoclonal antibody has shown some role in treatment Covid-19 infection. The study was cross-sectional prospective observational study. It conducted Intensive Care Unit (ICU) Liaquat National Hospital and Medical College, Centre Karachi. from 15th June 2020 31st July 2020. Objective compare outcomes severe established Cytokine release Syndrome (CRS), who received Tocilizumab group followed by intravenous immunoglobulins (IVIG). Two groups made receiving alone while other IVIG after Tocilizumab. Comparison then based on frequency mortality as well need mechanical ventilation its range days. In results 4 (15.4%) only died treated had 10 (38.46%) deaths. 20 (76.9%) needed consisted 23 (88.46%) patients. This concludes that therapy better outcome both immunoglobulins.
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ژورنال
عنوان ژورنال: International journal of infectious diseases and therapy
سال: 2021
ISSN: ['2578-9651', '2578-966X']
DOI: https://doi.org/10.11648/j.ijidt.20210601.15